What makes a good refrigerant?

Performance

suitability for target use and equipment type; capacity and efficiency → boiling point; critical temperature; heat of vaporisation; & stability at operating temperatures; materials compatibility.

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Safety

requirements for the specific application → flammability; toxicity; risk mitigation measures.

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Environmental effects

Climate change impact (refrigerant and energy related emissions); other environmental effects -VOC (POCP- photochemical ozone creation potential), atmospheric breakdown products; Zero or near-zero ODP; recyclability

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Refrigerant selection is made taking all the criteria of a refrigerant into account for a given application, as well as lifetime emissions from energy use and any refrigerant emissions.