According to the recently released 2010 France refrigerants survey – published by Mines ParisTech/Armines/ERIE for the French ADEME Agency (Inventaires des Emissions des fluides frigorigènes - FRANCE – Année 2010) - the French total demand for refrigerants was 10,224 tonnes in 2010, of which 80 % HFCs (mainly HFC-134a and R-404A), 15 % HCFCs (practically only HFCF-22) and 5 % ammonia and CO2.
HFO-1234yf was found to be a near drop-in refrigerant for HFC-134a and performing better than CO2 in tests run by a Spanish producer of bus air-conditioning systems, co-funded by the Spanish Science and Innovation Ministry.
German installers have evaluated the use of R407C and of CO2 in air/water domestic heat pumps, and concluded that R407C gives a better environmental performance than CO2 - measured as TEWI (Total equivalent Warming Impact).

A newly installed Organic Rankine Cycle (ORC), using a mixture of HFC-134a and HFC-245fa as working fluid, will deliver an additional 2.5 MW to the existing 16.7 MW capacity of a Geothermal Facility in Nevada, USA.

COOL-SAVE is an Intelligent Energy – Europe project, designed to develop and disseminate cost effective strategies to improve energy efficiency in cooling systems in the food and drink sector, the biggest manufacturing sector in the UE.
HFC-134a is used in water chillers necessary for the manufacture of high precision shafts produced in a French factory. This is a technically challenging process, starting from three meters long rods of different diameters which are machined to achieve high precision 6 to 40 mm diameter pieces.

An air-conditioning equipment manufacturer has evaluated R410A and CO2 in one of its units, and concludes that R410A performs better than CO2.