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Toxicological profile HFC-227ea

HFC-227ea (1,1,1,2,3,3,3-heptafluoropropane)

Acute toxicity Inhalation, LC 50, 4 h, rat

>11 %

Irritation

Rabbit, non irritant (eyes)
No irritation signs noted during toxicity testing

Inhalation, after a single exposure, dog

>= 10%, cardiac sensitization following adrenergic stimulation

Inhalation, after repeated exposure, rat

10%, no observed effect

Did not show mutagenic or teratogenic effects in animal experiments

Comments

no appreciable toxic effect

 

 

 

 

 

Source: Safety Data Sheet of Solvay

Updated: May 2008