HFC-143a (1,1,1-trifluoroethane)

Acute toxicity

Oral route, LD 50

not applicable

Dermal route, LD 50

not applicable

Inhalation, LC 50, 4 h, rat

> 60 %

Irritation

no irritation signs noted during toxicity testing

Sensitization

no data

Chronic toxicity

Inhalation, after a single exposure, dog

>= 30 %, cardiac sensitization following adrenergic stimulation

Inhalation, after prolonged exposure, rat

4 %, no observed effect

No mutagenic, carcinogenic, teratogenic effects

Comments

no appreciable toxic effect