Toxicological profile of HCFC-142b (1-chloro-1,1-difluoro-ethane)

Acute toxicity
Inhalation, LC 50, 4 h, rat : > 40 %

Irritation :
Rabbit, non irritant (eyes)

Chronic toxicity:
Inhalation, after a single exposure, dog: > 5 %, cardiac sensitization following adrenergic stimulation

No carcinogenic, teratogenic effects
In vitro, Ambiguous mutagenic effect
In vivo, no mutagenic effect

Comments:
Not hazardous in normal conditions of handling and use

Source
Safety Data Sheet of Solvay