Toxicological profile of HCFC-142b (1-chloro-1,1-difluoro-ethane)

Acute toxicity
Inhalation, LC 50, 4 h, rat : > 40 %

Irritation :
Rabbit, non irritant (eyes)

Chronic toxicity:
Inhalation, after a single exposure, dog: > 5 %, cardiac sensitization following adrenergic stimulation

No carcinogenic, teratogenic effects
In vitro, Ambiguous mutagenic effect
In vivo, no mutagenic effect

Not hazardous in normal conditions of handling and use

Safety Data Sheet of Solvay